Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

2.9K
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neurology in the Twenty-First Century.

Annals of neurology·2025
Same author

Amyotrophic Lateral Sclerosis, the Endocannabinoid System, and Exogenous Cannabinoids: Current State and Clinical Implications.

Muscle & nerve·2025
Same author

Occupational nerve injuries.

Muscle & nerve·2024
Same author

Fibrin Glue Acutely Blocks Distal Muscle Contraction after Confirmed Polyethylene Glycol Nerve Fusion: An Animal Study.

Plastic and reconstructive surgery. Global open·2024
Same author

Patient Reported Outcomes Using Medical Cannabis for Managing Pain in Charcot-Marie-Tooth Disease.

The American journal of hospice & palliative care·2023
Same author

Characterization of adult patients with Guillain-Barré syndrome during the arboviral infection outbreaks in Honduras.

Journal of the neurological sciences·2021
Same journal

Characterizing Combined Central and Peripheral Demyelination-Insights From a Multimodal Comparison With Chronic Inflammatory Demyelinating Polyneuropathy and Multiple Sclerosis.

Muscle & nerve·2026
Same journal

Electrical Modalities in the Rehabilitation of Peripheral Nerve Injuries: State of the Literature and Current Clinical Applications.

Muscle & nerve·2026
Same journal

Reply to "Sural/Radial Amplitude Ratio in Non-Length-Dependent Neuropathy (NLDN): A Call for More Standardized Methodology and Further Evaluation of Distal NLDN".

Muscle & nerve·2026
Same journal

Late-Onset Myasthenia Gravis: An Increasingly Frequent Clinical Entity With Distinctive Challenges.

Muscle & nerve·2026
Same journal

Clinical Characteristics and Treatment Management of Seronegative Myasthenia Gravis: A Systematic Review of the Literature.

Muscle & nerve·2026
Same journal

Muscle-Specific Kinase Signaling and Its Therapeutic Potential.

Muscle & nerve·2026
See all related articles

Related Experiment Video

Updated: Mar 11, 2026

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation
07:53

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation

Published on: September 13, 2015

22.9K

Is electrodiagnosic testing for polyneuropathy overutilized?

Elliot B Bodofsky1, Gregory T Carter2, John D England3

  • 1Department of Physical Medicine and Rehabilitation, Cooper University Health Care, 3 Cooper Plaza, Camden, New Jersey, 08103, USA.

Muscle & Nerve
|November 19, 2016
PubMed
Summary
This summary is machine-generated.

Electrodiagnostic (EDx) testing is appropriate for most patients presenting with new signs and symptoms of distal symmetric polyneuropathy (DSP). Studies show EDx testing frequently aids in diagnosis, management, and understanding pathology for DSP patients.

Keywords:
diagnosiselectrodiagnosisneuromuscular diseasepolyneuropathyutilization

More Related Videos

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
08:56

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies

Published on: October 7, 2021

3.5K
In Vivo Electrophysiological Measurement of the Rat Ulnar Nerve with Axonal Excitability Testing
04:56

In Vivo Electrophysiological Measurement of the Rat Ulnar Nerve with Axonal Excitability Testing

Published on: February 6, 2018

10.2K

Related Experiment Videos

Last Updated: Mar 11, 2026

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation
07:53

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation

Published on: September 13, 2015

22.9K
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
08:56

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies

Published on: October 7, 2021

3.5K
In Vivo Electrophysiological Measurement of the Rat Ulnar Nerve with Axonal Excitability Testing
04:56

In Vivo Electrophysiological Measurement of the Rat Ulnar Nerve with Axonal Excitability Testing

Published on: February 6, 2018

10.2K

Area of Science:

  • Neurology
  • Clinical Electrophysiology

Background:

  • Distal symmetric polyneuropathy (DSP) is a common clinical problem.
  • Electrodiagnostic (EDx) testing is frequently utilized for suspected DSP.

Purpose of the Study:

  • To evaluate the utility and appropriateness of EDx testing in patients with suspected DSP.
  • To address recent assertions questioning the yield of EDx testing in DSP.

Main Methods:

  • Review of peer-reviewed literature on EDx testing for DSP.
  • Analysis of studies supporting and questioning the use of EDx in DSP.

Main Results:

  • Most studies support the use of EDx testing for suspected DSP.
  • EDx testing often changes diagnosis and management.
  • EDx provides insights into pathology, severity, and prognosis.

Conclusions:

  • EDx testing is appropriate for the majority of patients with new DSP symptoms.
  • Evidence supports the broad utility of EDx testing in DSP evaluation.