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Updated: Mar 11, 2026
Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
Second premolar agenesis as a subclinical phenotype of isolated cleft palate
J P Schwartz1, R C M C Lauris2, G Dalbén3
1PhD resident, Orthodontic Department, Araraquara Dental School, Paulista State University, Araraquara, Brazil.
Objective:
To compare the prevalence of dental anomalies in patients with isolated cleft palate with or without hypodontia of the second premolar.
Setting And Sample Population:
A total of 653 patients with isolated cleft palate aged 8-12 years were divided into two groups: G1-subjects without hypodontia of second premolar (n = 546) and G2-subjects with hypodontia of at least one-second premolar (n = 107). The control group consisted of 107 non-cleft orthodontic patients.
Materials & Methods:
Panoramic and periapical radiographs and dental casts were used to analyze the presence of dental anomalies. Intergroup comparisons were performed using the chi-square test complemented by Proportion test and Bonferroni test.
Results:
G2 presented higher prevalence of hypodontia of other permanent teeth compared to G1 and control. Ectopic eruption of the maxillary canine and tooth transposition were more frequent in patients with a cleft compared to patients without a cleft, without statistical differences. Deciduous molar infra-occlusion and second premolar disto-angulation were less prevalent in G1 and G2 compared to the control group. G2 showed a higher prevalence of complete cleft palate than G1.
Conclusion:
Patients with cleft palate and second premolar agenesis showed increased prevalence of tooth agenesis and palatally displaced canines.
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