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Updated: Mar 11, 2026

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
Published on: April 18, 2025
Molecular Imaging and Precision Medicine in Dementia and Movement Disorders
Atul K Mallik1, Alexander Drzezga2, Satoshi Minoshima1
1Department of Radiology and Imaging Sciences, School of Medicine, University of Utah, Room: 1A71, 30 North 1900 East, Salt Lake City, UT 84132, USA.
Abstract:
Precision medicine (PM) has been defined as "prevention and treatment strategies that take individual variability into account." Molecular imaging (MI) is an ideally suited tool for PM approaches to neurodegenerative dementia and movement disorders (MD). Here we review PM approaches and discuss how they may be applied to other associated neurodegenerative dementia and MD. With ongoing major therapeutic research initiatives that include the use of molecular imaging, we look forward to established interventions targeted to specific molecular pathophysiology and expect the potential benefit of MI PM approaches in neurodegenerative dementia and MD will only increase.

