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Updated: Mar 11, 2026

Inspiratory Muscle Training as an Adjunct to the Treatment of Weaning Failure in Critically Ill Patients: A Practical Guide
Published on: January 30, 2026
When continuous positive airway pressure (CPAP) fails.
Jagdeep S Virk1, Bhik Kotecha1
1Royal National Throat Nose & Ear Hospital, London, UK.
Obstructive sleep apnoea (OSA), a condition linked to obesity, impacts health and the economy. Treatment options beyond continuous positive airway pressure (CPAP) and improving CPAP tolerance are explored for better patient outcomes.
Area of Science:
- Sleep Medicine
- Otolaryngology
- Public Health
Background:
- Obstructive sleep apnoea (OSA) prevalence is rising, exacerbated by the obesity epidemic, leading to significant health and economic burdens.
- Continuous positive airway pressure (CPAP) is the primary treatment for moderate to severe OSA, but patient compliance remains a challenge.
- Effective OSA management requires addressing treatment adherence and exploring alternative strategies.
Approach:
- This review discusses methods to enhance patient tolerance to CPAP therapy.
- It explores alternative non-surgical and surgical management options for OSA.
- The importance of upper airway evaluation by otolaryngologists for CPAP-intolerant patients is highlighted.
Key Points:
- Improving CPAP tolerance and exploring alternative treatments are crucial for managing OSA.
- Formal otolaryngological evaluation is recommended for patients who do not respond to CPAP.
- Identifying specific upper airway causes can guide site-specific surgical interventions.
- Careful patient selection is essential for successful treatment outcomes.
- A multidisciplinary team approach is necessary for comprehensive OSA patient management.
Conclusions:
- Addressing CPAP compliance and offering alternative therapies can improve OSA management.
- Surgical options guided by otolaryngological assessment offer potential benefits for select OSA patients.
- Multidisciplinary care optimizes outcomes for individuals with obstructive sleep apnoea.
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