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Updated: Mar 11, 2026

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
Published on: October 18, 2024
New endoscopic procedures for diabetes mellitus type 2 and obesity treatment
Francesco Frattini1, Giacomo Borroni1, Matteo Lavazza1
1Department of General Surgery, Endocrine Surgery Center, University of Insubria Varese, Varese, Italy.
Background:
Obesity continues to be a growing epidemic worldwide. Obese patients have severe comorbidities that make risky and technically demanding the execution of bariatric surgery from both surgical and anesthetic point of view; therefore, the focus of bariatric surgeons is increasingly moving towards minimally invasive, endoscopic techniques.
Methods:
The present review presents and discusses recent endoscopic techniques employed in obesity treatment, their features and results.
Results:
Endoscopic treatment can be primary or revisional; we can mainly divide the endoscopic devices into five categories: space-occupying devices, restrictive procedures, bypass liner, aspiration therapy and endoscopic revision of gastric bypass for dilated gastric pouch.
Conclusions:
Endoscopic treatments for obesity are promising techniques for selected patients but each procedure should be tailored on the patient in a multimodal approach.
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