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Cloning and expression analysis of a novel tissue-specific dopa decarboxylase mRNA splicing variant in Bombyx mori
Dai Tsukioka1,2, Susumu Izumi1, Takeshi Adachi1
1a Faculty of Science, Department of Biological Sciences , Kanagawa University , Hiratsuka , Japan.
Bioscience, Biotechnology, and Biochemistry
|November 22, 2016
Abstract:
Dopa decarboxylase (DDC) protein is involved in the synthesis of dopamine and serotonin. Here, we show that in the silkworm Bombyx mori, a novel DDC splicing variant is selectively expressed in the brain and subesophageal ganglia. In Drosophila melanogaster, a neuron-specific isoform of DDC is known to be alternatively spliced in a similar manner.
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