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Putting the Barker Theory into the Future: Time to Act on Preventing Pediatric Obesity
Angelo Pietrobelli1,2, Massimo Agosti3, Gianvincenzo Zuccotti4
1Pediatric Unit, Università degli Studi di Verona, Piazzale L.A. Scuro 10, 37134 Verona, Italy. angelo.pietrobelli@univr.it.
Insights
Preventing childhood obesity is crucial during the first 1000 days of life. Research highlights key factors and strategies for healthy growth and development in early childhood.
Area of Science:
- Pediatric Nutrition and Health
- Developmental Biology
- Obesity Prevention Science
Background:
- The first 1000 days (conception to 24 months) are critical for child development and health.
- Childhood growth and development are sensitive indicators of nutrition and overall well-being.
- Preventing early-life obesity is mandatory to avoid long-term adverse health consequences.
Discussion:
- Growth is influenced by nutrition, genetics, epigenetics, and hormonal regulation.
- Maximizing growth potential while mitigating obesity risk is a key challenge.
- The Mediterranean Nutrition Group (MeNu Group) presented findings on early-life obesity risk factors.
Key Insights:
- Studies in humans and animal models advanced understanding of obesity risk factors in early life.
- Interventions must consider multiple growth drivers during this sensitive developmental period.
- The MeNu Group's research offers insights into preventing pediatric obesity.
Outlook:
- Future interventions for pediatric obesity prevention require diverse strategies.
- Developing appropriate conceptual frameworks is essential for effective prevention and treatment.
- The MeNu Group is positioned to guide future research and interventions in early-life obesity prevention.
Abstract:
Growth and development are key characteristics of childhood and sensitive markers of health and adequate nutrition. The first 1000 days of life-conception through 24 months of age-represent a fundamental period for development and thus the prevention of childhood obesity and its adverse consequences is mandatory. There are many growth drivers during this complex phase of life, such as nutrition, genetic and epigenetic factors, and hormonal regulation. The challenge thus involves maximizing the potential for normal growth without increasing the risk of associated disorders. The Mediterranean Nutrition Group (MeNu Group), a group of researchers of the Mediterranean Region, in this Special Issue titled "Prevent Obesity in the First 1000 Days", presented results that advanced the science of obesity risk factors in early life, coming both from animal model studies and studies in humans. In the future, early-life intervention designs for the prevention of pediatric obesity will need to look at different strategies, and the MeNu Group is available for guidance regarding an appropriate conceptual framework to accomplish either prevention or treatment strategies to tackle pediatric obesity.
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