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Published on: February 10, 2023
Urolithiasis in inflammatory bowel disease and bariatric surgery
Agapios Gkentzis1, Michael Kimuli1, Jon Cartledge1
1Agapios Gkentzis, Michael Kimuli, Jon Cartledge, Chandra Shekhar Biyani, Department of Urology, St James's University Hospital, Leeds LS9 7TF, United Kingdom.
Aim:
To analyse current literature focusing on pathogenesis and therapeutic aspects of urolithiasis with inflammatory bowel disease (IBD) and following bariatric surgery.
Methods:
A systematic literature search was performed using PubMed, supplemented with additional references. Studies assessing the association of IBD or bariatric surgery with renal stones in both paediatric and adulthood were included.
Results:
Certain types of stones are seen more frequently with IBD. Hyperoxaluria and hypocitraturia are the main metabolic changes responsible for urolithiasis. The incidence of renal stones in malabsorptive types of bariatric surgery such as gastric bypass is high; this is not as common in modern restrictive surgical methods. Preventative methods and urine alkalinisation have been shown to be beneficial.
Conclusion:
Both conditions are associated with renal stones. Patients' counselling and prevention strategies are the mainstay of urolithiasis management in these patients.
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