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Updated: Mar 11, 2026

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors
Published on: February 10, 2014
Reversible pH-independent optical potassium sensor with lipophilic solvatochromic dye transducer on surface modified
Lu Wang1, Xiaojiang Xie1, Jingying Zhai1
1University of Geneva, 30 Quai Ernest Ansermet, 1211 Geneva 4, Switzerland. eric.bakker@unige.ch.
Abstract:
A reversible and pH-independent fluorescent ion optode is introduced with an ionophore and surface confined solvatochromic dye transducer doped onto microporous nylon membranes. The resulting film responds to K+ with excellent selectivity over the range of 10-7 to 10-2 M and a response time of t95 < 60 s above 10-6 M.
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