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Related Concept Videos

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
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Related Experiment Video

Updated: Mar 11, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
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Evolution of multiple sclerosis spasticity-associated symptoms: latest data.

Peter Flachenecker1

  • 1Neurological Rehabilitation Center Quellenhof, Bad Wildbad, Germany.

Neurodegenerative Disease Management
|November 23, 2016
PubMed
Summary

For multiple sclerosis (MS) spasticity, an oral spray containing 9-delta-tetrahydrocannabinol:cannabidiol shows promise. This treatment offers a positive risk:benefit profile for patients with resistant symptoms.

Area of Science:

  • Neurology
  • Pharmacology
  • Cannabinoid Science

Background:

  • Multiple sclerosis (MS) spasticity presents with diverse symptoms including muscle stiffness, spasms, and mobility limitations.
Keywords:
antispasticity drugsclinical trialsmultiple sclerosisobservational studiesregistry studiesspasticity-associated symptoms

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  • Current treatments like baclofen, tizanidine, and gabapentin have low patient and physician satisfaction.
  • Resistant MS spasticity significantly impacts daily functioning and quality of life.