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Phthalate levels and related factors in children aged 6-12 years

Wei Wu1, Feng Zhou2, Yue Wang2

  • 1School of Laboratory Medicine, Hubei University of Chinese Medicine, 1 Huangjia Lake West Road, Wuhan 430065, China.

Environmental Pollution (Barking, Essex : 1987)
|November 24, 2016
PubMed

Insights

This study identified key sources of phthalate exposure in Chinese school-aged children, linking housing, toys, and diet to phthalate metabolite levels. Reducing exposure involves avoiding plastics, fragrances, and processed foods, especially canned items.

Area of Science:

  • Environmental Health
  • Pediatric Toxicology

Background:

  • Phthalate exposure is common in children, but sources for school-aged Chinese children remain unclear.
  • Understanding exposure pathways is crucial for public health interventions.

Purpose of the Study:

  • To assess phthalate metabolite levels in Chinese school-aged children.
  • To identify factors influencing phthalate exposure in this population.

Main Methods:

  • Collected demographic data and urine samples from 336 children (aged 6-12 years).
  • Measured 14 mono-phthalate metabolites using urinary concentrations.
  • Employed chi-square tests and logistic regression to analyze exposure factors.

Main Results:

  • Mono-n-butyl phthalate (MnBP) and mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) were the most prevalent metabolites.
  • Low molecular weight phthalate exposure linked to housing type, decorating materials, and canned food.
  • High molecular weight phthalate exposure linked to water source, toy play duration, residential area, and canned food consumption.

Conclusions:

  • Housing, home materials, diet (canned foods), water source, and toy use are significant factors for phthalate exposure in children.
  • Recommendations include reducing use of plastic containers/packaging, avoiding chemical fragrances, and limiting processed/canned food intake.

Keywords:
Phthalate metaboliteRelate factorsSchool-aged children

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