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Updated: Mar 11, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
[Mechanisms of reparative action of a new repair and protect toothpaste]
T M Elovikova1, E Yu Ermishina1, N I Mikheikina1
1Ural State Medical University, Yekaterinburg, Russia.
Abstract:
The aim of the study was to assess clinical efficacy of Sensodyne repair and protect toothpaste as well as mechanics of its reparative action. Forty-eight patients (29 females and 19 males) were included in the study. The participants brushed twice daily with Sensodyne toothpaste. In 24 patients in addition to clinical examination fluoride, calcium and pH were measured in oral fluid. The study showed OHIS reduction by 40.24% and eradication of tooth hypersensitivity even after single use of the toothpaste in 90% of patients because of sodium monofluorophosphate action.
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