[Specific immunotherapy applied in the otorhionolaryngological practice]

Area of Science:

• Otolaryngology
• Allergology
• Immunology

Background:

• Allergic rhinitis and other Ear, Nose, and Throat (ENT) diseases pose significant challenges in clinical practice.
• Pharmacotherapy is a common treatment, but may have limitations and side effects.
• Specific immunotherapy (SIT) presents an alternative treatment modality.

Purpose of the Study:

• To establish evidence-based indications for specific immunotherapy (SIT) in ENT diseases.
• To evaluate the efficacy and safety of SIT compared to pharmacotherapy.
• To provide guidance on managing adverse reactions associated with SIT.

Main Methods:

• Retrospective analysis of 1058 patients with allergic rhinitis treated with SIT.
• Comparison of treatment outcomes between SIT and pharmacotherapy.
• Documentation and analysis of adverse events and their corrective measures.

Main Results:

• Specific immunotherapy (SIT) demonstrated advantages over traditional pharmacotherapy for allergic rhinitis.
• Established clear indications for the use of SIT in otolaryngological practice.
• Identified and outlined methods for managing adverse reactions to SIT.

Conclusions:

• Specific immunotherapy (SIT) is a valuable treatment option for allergic rhinitis and other ENT conditions.
• Careful patient selection and management of adverse reactions are crucial for successful SIT.
• SIT offers a promising alternative to pharmacotherapy in otolaryngology.