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Updated: Mar 11, 2026

Quantification of Cellular Densities and Antigenic Properties using Magnetic Levitation
Published on: May 17, 2021
Observations of cellular responses to diamagnetic forces acting on cell components
Masakazu Iwasaka1, Kentaro Suzuki2, Tadashi Sugawara2
1Graduate School of Engineering, Chiba University, Inage-ku, Chiba 263-8522, Japan.
Abstract:
The magnetooptical measurements of the properties of living cells have a potentially large impact on cellular engineering and biotechnology because the noninvasive approach to applying magnetic fields on cells enables the detection of the dynamics of intracellular components under natural conditions. In this study, we examine a magnetooptical response in smooth muscle cells exposed to a vertical magnetic field of 5 T. The time course of the linearly polarized light transmittance of cells showed both a gradual decrease and fluctuations during exposure at 5 T. Real-time observations of smooth muscle cells and giant rodlike vesicles revealed that magnetic fields cause morphological changes in the cells and vesicles. In addition, results of the optical transmittance measurement of a fish scale indicate that cellular or tissue components are diamagnetically reoriented by magnetic fields.
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