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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Implications of Preterm Birth for Maternal Mental Health and Infant Development
Cheryl Anderson1, Priscila Cacola
1Cheryl Anderson is an Associate Professor, College of Nursing & Health Innovation, College of Nursing, University of Texas at Arlington, Arlington, TX. The author can be reached via e-mail at c.anderson@uta.edu Priscila Cacola is an Assistant Professor, College of Nursing & Health Innovation, Department of Kinesiology, University of Texas at Arlington, Arlington, TX. The author can be reached via e-mail at cacola@uta.edu.
Insights
Maternal mental health issues like depression and posttraumatic stress disorder (PTSD) after preterm birth can impact infant development and mother-infant bonding. Early interventions are crucial for both maternal well-being and infant outcomes.
Area of Science:
- Perinatal mental health
- Infant development
- Mother-infant attachment
Background:
- Preterm birth is a leading cause of infant mortality and morbidity, including developmental delays.
- Maternal mental health issues, such as depression and posttraumatic stress disorder (PTSD), are common after preterm birth and affect maternal-infant bonding.
- Maternal distress is a consistent factor influencing infant development.
Purpose of the Study:
- To review the relationship between maternal depression and PTSD following preterm birth, and their effects on mother-infant attachment and infant development.
- To highlight the importance of prenatal and postpartum interventions for maternal mental health and infant outcomes.
- To explore the role of PTSD, a condition gaining recent research attention, in impaired maternal-infant attachment and infant motor development.
Main Methods:
- Literature review examining studies on maternal mental health post-preterm birth.
- Analysis of the impact of maternal depression and PTSD on mother-infant attachment.
- Review of potential assessments and interventions for mothers and infants affected by preterm birth.
Main Results:
- Maternal depression and PTSD are linked to impaired mother-infant attachment and can negatively affect infant development.
- While depression has been extensively studied, the impact of PTSD on infant motor development requires further investigation.
- Early mother-infant interactions are influenced by both prematurity and maternal mental health.
Conclusions:
- Healthcare professionals must intervene prenatally and postpartum to address maternal distress, which significantly impacts infant development.
- Home-based interventions that stimulate infant development and strengthen the mother-infant relationship may reduce maternal depression and PTSD symptoms.
- Targeted interventions are essential for improving infant development and maternal well-being, fostering a healthier mother-infant dyad.
Abstract:
Preterm birth remains a major contributor to infant mortality and morbidity including neurodevelopmental delay and childhood disability. Mothers experiencing a preterm birth are at risk for maternal mental health issues, inclusive of depression and posttraumatic stress disorder (PTSD), which may affect mother-infant attachment and infant development. Depression and PTSD, frequently comorbid, following preterm birth and relationships between these symptoms, maternal-infant attachment, and infant development are reviewed. Assessments and interventions potentially capable of benefitting mother and infant are noted. The need for healthcare professionals to intervene prenatally and at postpartum is significant as maternal distress remains one of the most consistent factors related to infant development. Although depression has received much attention in the literature as a risk factor for preterm birth, impaired attachment, and delayed infant development, some of the consequences of PTSD have only recently gained research attention. A few studies support the role of PTSD in impaired maternal-infant attachment; yet, it is unclear whether preterm infants of mothers experiencing symptoms of PTSD following birth are at a higher risk for motor development problems. Because early mother-infant interactions are influenced by prematurity as well as maternal mental health, consideration for home interventions that stimulate infant development and encourage mother-infant relationships concurrently are important. Directed interventions may be beneficial for infant development and aid in strengthening the mother-infant relationship, potentially reducing depression and PTSD symptoms in the mother.
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