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Published on: May 22, 2019
Alcohol and stroke: the splitters win again
Arthur L Klatsky1, H Nicole Tran2
1Division of Research, Northern California Kaiser Permanente, 2000 Broadway, Oakland, CA, 94612, USA. hartmavn@pacbell.net.
Abstract:
Study of the relationships of alcohol drinking and risk of stroke can readily become mired in the labyrinthine interactions of drinking categorizations, non-linear associations, disparate cardiovascular conditions, and the heterogeneous types of stroke. This Commentary discusses the recent article by Larsson et al. (BMC Medicine 14:178, 2016). The authors split their material into separate meta-analyses of subarachnoid hemorrhage, intracerebral hemorrhage, and ischemic stroke, finding disparate alcohol-stroke relationships. Our Commentary pursues the disparity theme, using the lumpers versus splitters paradigm to explore several aspects of this complex area.Please see related article: http://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-016-0721-4 .
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