Related Experiment Video
Updated: Mar 11, 2026

Quantitative Metabolomics of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry
Published on: January 5, 2021
Application of THz Vibrational Spectroscopy to Molecular Characterization and the Theoretical Fundamentals: An
Feng Zhang1, Houng-Wei Wang2, Keisuke Tominaga1
1Molecular Photoscience Research Center, Kobe University, Kobe, 657-8501, Japan.
Abstract:
This work illustrates several theoretical fundamentals for the application of THz vibrational spectroscopy to molecular characterization in the solid state using two different types of saccharide systems as examples. Four subjects have been specifically addressed: (1) the qualitative differences in the molecular vibrational signatures monitored by THz and mid-IR vibrational spectroscopy; (2) the selection rules for THz vibrational spectroscopy as applied to crystalline and amorphous systems; (3) a normal mode simulation, using α-l-xylose as an example; and (4) a rigorous mode analysis to quantify the percentage contributions of the intermolecular and intramolecular vibrations to the normal mode of interest.
Related Concept Videos
Chemistry of Carbohydrates
Chemistry of Carbohydrates
IR Spectroscopy: Molecular Vibration Overview
Stretching vibrations are vibrational motions that occur along the bond line, changing the bond length or distance between two bonded atoms. They are further distinguished as symmetric or asymmetric. In symmetric stretching, the...
Spectroscopy of Carboxylic Acid Derivatives
Raman Spectroscopy: Overview
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
Molecular Spectroscopy: Absorption and Emission

