Related Experiment Video
Updated: Mar 11, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Tuberculosis and the Heart
Arthur K Mutyaba1, Mpiko Ntsekhe1
1Division of Cardiology, Department of Medicine, Groote Schuur Hospital, University of Cape Town, E17 Cardiac Clinic, New Groote Schuur Hospital, Anzio Road, Observatory 7925, Cape Town, South Africa.
Tuberculous heart disease, common in TB-endemic regions, requires updated management strategies. Recent research offers improved evidence-based approaches to reduce its significant morbidity and mortality.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Tuberculous heart disease is a significant concern in areas with high rates of tuberculosis (TB) and human immunodeficiency virus/AIDS.
- Traditional management approaches need updating due to recent research findings.
Purpose of the Study:
- To review and update the understanding of tuberculous heart disease.
- To provide current evidence-based strategies for pathophysiology, diagnosis, and treatment.
Main Methods:
- Review of recent clinical and basic science research over the past decade.
- Synthesis of traditional knowledge with new findings.
Main Results:
- Updated insights into the pathophysiology of tuberculous heart disease.
- Enhanced diagnostic criteria and treatment protocols.
Conclusions:
- Implementing updated, evidence-based approaches can significantly decrease the morbidity and mortality associated with tuberculous heart disease.
- Further progress in managing this condition is achievable with widespread adoption of new strategies.
Related Concept Videos
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Rheumatic Heart Disease I: Introduction

