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Published on: August 22, 2025
[Descriptive analysis of 660 cases of upper digestive hemorrhage: relation of emergency endoscopy and mortality]
Insights
Early endoscopy is crucial for diagnosing upper gastrointestinal bleeding (UGIB) and assessing patient prognosis. This study highlights peptic ulcers as a common cause, emphasizing timely endoscopic evaluation for better outcomes.
Area of Science:
- Gastroenterology
- Internal Medicine
- Clinical Research
Context:
- Upper gastrointestinal bleeding (UGIB) is a significant clinical challenge.
- Endoscopic findings are vital for diagnosing the cause of UGIB.
- Patient demographics and risk factors influence outcomes.
Purpose:
- To analyze endoscopic findings in patients with upper gastrointestinal bleeding.
- To identify the primary causes of UGIB and associated risk factors.
- To evaluate the prognostic value of early endoscopy in UGIB management.
Summary:
- A study of 660 patients with upper gastrointestinal bleeding (UGIB) found peptic ulcers to be the most common cause.
- Early gastroscopy (within 24 hours) was performed in 77.4% of cases.
- Global mortality was 3.6%, with surgical mortality at 13.5%.
Impact:
- Emphasizes the need for early endoscopy in diagnosing and predicting prognosis for upper gastrointestinal bleeding.
- Highlights the importance of identifying risk factors and common etiologies like peptic ulcers.
- Supports the integration of endoscopic findings into risk stratification for UGIB patients.
Abstract:
A study was made of 660 patients admitted for upper gastrointestinal bleeding in which the endoscopic findings were analyzed, excluding patients with esophageal varices and cases in which the lesions responsible for bleeding were not appreciated (5.7% diagnostic failure). 71.7% were males and 38.3% females, average age was 59.9 +/- 17.5 years and average hematocrit on admission was 27.4 +/- 8.2. 58.3% were over 60 years-old. There was a history of ingestion of gastro-erosive drugs in 56.8%. Gastroscopy was performed within 24 hours of admission in 77.4%, the first clinical symptom of bleeding being melenas in 50%. Peptic ulcer was the most common cause of upper gastrointestinal bleeding. Eighty-one patients required surgery, 30 early and 51 delayed. The global mortality was 3.6% and surgical mortality, 13.5%. After relating the endoscopic groups of upper gastrointestinal bleeding and individual risk with mortality rates, emphasis is placed on the need for early endoscopy as a diagnostic tool of prognostic value.
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