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Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
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Pediatric Inflammatory Bowel Disease.

Akshay Kapoor1, Vidyut Bhatia, Anupam Sibal

  • 1Department of Pediatric Gastroenterology, Apollo Centre for Advanced Pediatrics, Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India. Correspondence to: Dr Akshay Kapoor, Department of Pediatric Gastroenterology, Hepatology and Liver Transplantation, Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India. akshaydr80@yahoo.co.in.

Indian Pediatrics
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Summary
This summary is machine-generated.

Pediatric inflammatory bowel disease (IBD) is rising globally, impacting growth and quality of life. Current guidelines, adapted from adult data, are evolving with new treatments to focus on healing and normal development.

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Area of Science:

  • Pediatric Gastroenterology
  • Inflammatory Bowel Disease Research
  • Clinical Guidelines

Background:

  • Increasing global incidence of inflammatory bowel disease (IBD) in children.
  • Limited high-quality scientific data specific to pediatric IBD.
  • Adaptation of adult guidelines for pediatric diagnosis and treatment due to small patient cohorts and limited multicentric trials.

Purpose of the Study:

  • To review and amalgamate principles for diagnosing and managing pediatric inflammatory bowel disease.
  • To address the paucity of specific scientific data and guidelines for pediatric IBD.
  • To provide a comprehensive overview for clinicians managing children with suspected IBD.

Main Methods:

  • Comprehensive literature search using electronic databases (PubMed, OVID).
  • Inclusion of keywords: pediatric, inflammatory bowel disease, Crohn's disease, ulcerative colitis, epidemiology, and guidelines.
  • Synthesis of existing knowledge on diagnosis and management principles.

Main Results:

  • Children and young adolescents constitute 25% of all IBD patients.
  • Key concerns include impact on growth velocity, puberty, and psychosocial well-being.
  • Treatment strategies are evolving with increased therapeutic options.

Conclusions:

  • Emphasis on achieving mucosal healing and normalizing growth velocity.
  • Minimizing drug toxicity is a primary treatment goal.
  • Ongoing redefinition of treatment guidelines for pediatric IBD is necessary.