Prediction of Massive Transfusion in Trauma
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Updated: Mar 11, 2026

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Published on: November 8, 2024
Paul M Cantle1, Bryan A Cotton1
1Department of Surgery, University of Texas Mcgovern Medical School, 6431 Fannin, Room 4.286, Houston, TX 77030, USA.
Hemorrhage is the leading cause of preventable death in trauma. Damage control resuscitation relies on permissive hypotension, minimizing crystalloid use, and early implementation of massive transfusion protocols with established blood component ratios. These protocols improve the survival of the severely injured patient. Trauma physicians must quickly and accurately predict when a massive transfusion protocol should be activated. Several validated transfusion scores have been developed for this purpose. Many of these scores are useful for resuscitation research. One option, the ABC score, is an accurate, validated, and clinically useful score that is simple to calculate and rapidly obtained.
Hemorrhage is the leading cause of preventable death in trauma. Damage control resuscitation relies on permissive hypotension, minimizing crystalloid use, and early implementation of massive transfusion protocols with established blood component ratios. These protocols improve the survival of the severely injured patient. Trauma physicians must quickly and accurately predict when a massive transfusion protocol should be activated. Several validated transfusion scores have been developed for this purpose. Many of these scores are useful for resuscitation research. One option, the ABC score, is an accurate, validated, and clinically useful score that is simple to calculate and rapidly obtained.
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