Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 11, 2026

Assessing the Secretory Capacity of Pancreatic Acinar Cells
09:52

Assessing the Secretory Capacity of Pancreatic Acinar Cells

Published on: August 28, 2014

17.7K

Quantitative Estimation of Parietal Cell Secretory Function in Man.

Paul Rødbro1,2, Poul M Christiansen1

  • 1a Medical Department F, Glostrup Hospital, and Surgical Department A , Bispebjerg Hospital , Copenhagen , Denmark.

Scandinavian Journal of Gastroenterology
|November 30, 2016
PubMed
Summary

Gastric secretory patterns vary across conditions. Duodenal ulcer patients show increased acid and intrinsic factor secretion, while atrophic gastritis and pernicious anemia patients exhibit reduced or abolished parietal cell function.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Single Gastric Biopsy in Subjects with Low Acid Secretion after Maximal Histamine Stimulation.

Scandinavian journal of gastroenterology·2016
See all related articles

Area of Science:

  • Gastroenterology
  • Physiology

Background:

  • Gastric secretion analysis is crucial for understanding digestive health.
  • Parietal cell function impacts acid and intrinsic factor production.

Purpose of the Study:

  • To describe and compare gastric secretory patterns.
  • To investigate differences in patients with duodenal ulcer, atrophic gastritis, and pernicious anemia.

Main Methods:

  • Maximal histamine stimulation was used.
  • Measurements included gastric volume, acid, and intrinsic factor secretion.

Main Results:

  • Duodenal ulcer patients had higher acid and intrinsic factor secretion than healthy individuals, with identical patterns but greater volume due to increased parietal cell mass.
Keywords:
Stomachanemia, perniciousduodenal ulcergastric acidity determinationgastric juiccgastritishydrochloric acidintrinsic factor

More Related Videos

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice
14:39

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice

Published on: January 9, 2026

681
Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine
07:00

Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine

Published on: February 26, 2019

10.1K

Related Experiment Videos

Last Updated: Mar 11, 2026

Assessing the Secretory Capacity of Pancreatic Acinar Cells
09:52

Assessing the Secretory Capacity of Pancreatic Acinar Cells

Published on: August 28, 2014

17.7K
A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice
14:39

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice

Published on: January 9, 2026

681
Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine
07:00

Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine

Published on: February 26, 2019

10.1K
  • Atrophic gastritis patients showed decreased acid and intrinsic factor secretion, with acid reduction more pronounced than intrinsic factor.
  • Pernicious anemia patients exhibited abolished parietal cell function.

    • Conclusions:

    • Gastric secretory patterns differ significantly across various gastrointestinal conditions.
    • Findings suggest potential dissociation of secretory components in hyposecretory states.
    • Parietal cell function is severely impaired in pernicious anemia.