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Optical Microbubble Resonators with High Refractive Index Inner Coating for Bio-Sensing Applications: An Analytical

Andrea Barucci1, Simone Berneschi2, Ambra Giannetti3

  • 1Istituto di Fisica Applicata Nello Carrara (CNR IFAC), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Firenze, Italy. a.barucci@ifac.cnr.it.

Sensors (Basel, Switzerland)
|November 30, 2016
PubMed
Summary
This summary is machine-generated.

We present a new design method for optical microbubble resonators (OMBRs) to improve biosensor sensitivity and detection limits. This involves adding a high refractive index polymer layer to enhance performance.

Keywords:
high refractive index polymeroptical microbubble resonatoroptical modelingwhispering gallery mode resonators

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Area of Science:

  • Optics
  • Biotechnology
  • Materials Science

Background:

  • Whispering Gallery Mode Resonators (WGMRs) are vital optical transducers for biosensing.
  • Optimizing WGMR design is critical for enhancing sensitivity and Limit of Detection (LoD).

Purpose of the Study:

  • To propose an analytical method for designing optical microbubble resonator (OMBR)-based biosensors.
  • To enhance OMBR sensing performance by incorporating a high refractive index polymeric inner coating.

Main Methods:

  • Analytical modeling of OMBR design.
  • Assessment of optical and geometrical parameters' effects.
  • Analysis of mode field distribution, sensitivity, and LoD for TE and TM polarizations.

Main Results:

  • The proposed analytical method provides insights into OMBR design optimization.
  • A high refractive index polymeric layer significantly impacts OMBR performance.
  • Sensitivity and LoD are analyzed concerning various design parameters and polarizations.

Conclusions:

  • The study offers a pathway for developing high-performance OMBR-based biosensors.
  • Physical insights gained can guide future OMBR sensor development.
  • The analytical method facilitates optimized design for improved biosensing capabilities.