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Updated: Mar 11, 2026

Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
Published on: May 27, 2011
[Tocilizumab treatment of HHV8-positive/HIV-negative, multricentric plasma cell type Castleman's disease]
Györgyi Mûzes1, Judit Csomor2, Ferenc Sipos1
1II. Sz. Belgyógyászati Klinika, Semmelweis Egyetem, Budapest, Hungary. muzes.gyorgyi@med.semmelweis-univ.hu.
Abstract:
This is a case presentation of a HHV8-positive multicentric Castleman's disease (MCD) of plasma cell type. The patient failed to respond to combined immunosuppressive therapy and monoclonal anti-CD20 therapy. Interestingly, administration of anti-IL-6R antibody stabilized the disease and resulted in clearance of HHV8 from the involved lymph nodes.
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