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Related Concept Videos

Fetal Circulation01:14

Fetal Circulation

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Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
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During early development, the embryo forms two types of connective tissues— the mesenchyme and mucoid connective tissue.
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Related Experiment Video

Updated: Mar 11, 2026

Author Spotlight: Advancements in Stem Cell-Derived Vascularized Organoids and Optimized Isolation of Wharton's Jelly for Enhanced MSC Production
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Lean Umbilical Cord - a Case Report.

N Rippinger1, M Elsässer1, P Sinn2

  • 1Universitäts-Frauenklinik, Frauenheilkunde und Geburtshilfe, Universitätsklinikum Heidelberg, Heidelberg, Germany.

Geburtshilfe Und Frauenheilkunde
|December 2, 2016
PubMed
Summary
This summary is machine-generated.

The rare "lean" umbilical cord, or thin-cord syndrome, was identified as a potential cause of acute placental insufficiency in a pregnant patient. This case highlights the importance of considering rare umbilical cord anomalies in obstetric emergencies.

Keywords:
Whartonʼs jellyplacental insufficiencythin-cord syndromeumbilical cord anomaly

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Area of Science:

  • Obstetrics and Gynecology
  • Fetal Medicine
  • Perinatal Research

Background:

  • The lean umbilical cord, also known as thin-cord syndrome, is a rare umbilical cord anomaly.
  • Limited medical literature exists describing this condition and its potential complications.

Purpose of the Study:

  • To report a case of acute placental insufficiency associated with a lean umbilical cord.
  • To highlight the diagnostic and management considerations for this rare condition.

Main Methods:

  • Case report of a 35-year-old woman presenting with vaginal bleeding and cervical incompetence at 29+4 weeks gestation.
  • Evaluation included sonography to exclude other causes of placental compromise.
  • Emergency cesarean section performed at 31+2 weeks gestation due to acute placental insufficiency.

Main Results:

  • The patient experienced premature rupture of membranes and acute placental insufficiency.
  • Intraoperative findings revealed a macroscopically extremely thin umbilical cord as the only notable anomaly.
  • Other common causes of placental insufficiency were excluded preoperatively.

Conclusions:

  • A lean umbilical cord may be associated with severe obstetric complications, including acute placental insufficiency.
  • This case underscores the need for increased awareness and consideration of rare umbilical cord anomalies in clinical practice.
  • Further research is warranted to understand the pathophysiology and long-term implications of thin-cord syndrome.