Related Experiment Video
Updated: Mar 11, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
Topical Therapy in Atopic Dermatitis in Children
Dharshini Sathishkumar1, Celia Moss2
1Department of Paediatric Dermatology, Birmingham Children's Hospital, Birmingham, UK.
Managing childhood atopic dermatitis (AD) involves a multifaceted approach. This review details topical treatments, focusing on patient education, barrier repair, and inflammation control for better quality of life.
Area of Science:
- Dermatology
- Pediatrics
- Immunology
Background:
- Atopic dermatitis (AD) is a prevalent, chronic skin condition in children.
- It results from complex genetic, immunological, and environmental factors.
- AD significantly impacts the quality of life for children and their families.
Purpose of the Study:
- To review the management of atopic dermatitis in children using topical treatments.
- To emphasize a personalized approach considering individual, social, and emotional factors alongside disease severity.
Main Methods:
- This review focuses on topical management strategies for pediatric atopic dermatitis.
- Key areas covered include patient/caregiver education, trigger avoidance, and skin barrier repair.
- Management of inflammation, infection, and adjunctive therapies like bandages are also discussed.
Main Results:
- Effective management requires a comprehensive strategy tailored to each child.
- Patient and caregiver education empowers them in managing the condition.
- Consistent use of emollients is crucial for skin barrier repair and maintenance.
Conclusions:
- Topical treatments, including corticosteroids and calcineurin inhibitors, are central to controlling inflammation in pediatric AD.
- Minimizing infection and utilizing supportive measures like bandages can improve outcomes.
- A holistic approach integrating medical treatment with psychosocial support is essential for managing childhood atopic dermatitis effectively.
Related Concept Videos
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Antiasthma Drugs: Leukotriene Modifiers
Leukotriene modifiers work through two distinct mechanisms:
Drug Dosing: Infants and Children
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Ophthalmic Drug Delivery Systems

