The Relationship of Psoriasis and Melanocytic Nevi
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Updated: Mar 11, 2026
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Fatma Pelin Cengiz1, Nazan Emiroglu1, Anil Gulsel Bahali1
1Department of Dermatology, Bezmialem Vakif University, Istanbul, Turkey.
Background:
There is limited data about the relationship between psoriasis and melanocytic lesions and melanoma. Immunologic pathways which were implicated in psoriasis induce a reduction in the number of melanocytic nevi.
Aims And Objectives:
To investigate the number of melanocytic nevi in psoriatic patients compared with controls and its relationship with disease severity and type of treatment.
Methods:
We performed a prospective study in 100 psoriatic patients and 100 controls. Clinical data were recorded for all participants.
Results:
As compared with controls, patients had overall fewer nevi congenital nevi. Among psoriatic patients, biologic agents and disease severity did not correlate with the number of nevi.
Conclusions:
Psoriatic patients have fewer nevi than controls. Frequency of nevi in psoriatic patients is not related to treatment and disease severity.
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