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[Propafenone per os in ventricular arrhythmia]
1Service de soins intensifs, Centre hospitalier de Chalon-sur-Saône.
Cahiers D'Anesthesiologie
|June 1, 1989
Summary
Oral propafenone effectively treats ventricular rhythm disorders in intensive care patients. This antiarrhythmic medication is generally well-tolerated, showing good results for most patients with cardiac arrhythmias.
Area of Science:
- Cardiology
- Pharmacology
Context:
- Ventricular rhythm disorders are a common critical care concern.
- Effective management of arrhythmias is crucial for patient outcomes.
Purpose:
- To evaluate the efficacy and tolerability of oral propafenone in intensive care unit (ICU) patients with ventricular arrhythmias.
Summary:
- Twenty-one ICU patients with ventricular rhythm disorders received oral propafenone (450-900 mg/hour).
- Excellent results were observed in 13 patients, with average results in 2, and no effect in 4.
- Two cases showed arrhythmia worsening; drug discontinuation occurred in two cases due to side effects (gastrointestinal upset, QRS broadening).
Impact:
- Oral propafenone demonstrates good tolerability and efficacy in treating ventricular arrhythmias of various causes.
- This finding supports propafenone as a viable treatment option for managing these cardiac conditions in critical care settings.