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Related Concept Videos

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We describe here, the establishment and application of an Tg(Myh6-cre)1Jmk/J /Gt(ROSA)26Sortm38(CAG-GCaMP3)Hze/J (referred to as αMHC-Cre/Rosa26A-Flox-Stop-Flox-GCaMP3 below) mouse reporter line for cardiac reprogramming assessment. Neonatal cardiac fibroblasts (NCFs) isolated from the mouse strain are converted into induced cardiomyocytes (iCMs), allowing for convenient and efficient evaluation of reprogramming efficiency and functional maturation of iCMs via calcium (Ca2+)...
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Related Experiment Video

Updated: Jan 20, 2026

In vitro Assessment of Cardiac Reprogramming by Measuring Cardiac Specific Calcium Flux with a GCaMP3 Reporter
05:04

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Published on: February 22, 2022

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Isolated cardiac peripheral primitive neuroectodermal tumor: A case report.

Chengming Fan1, Demiao Kong1, Changming Tan1

  • 1a Department of The Cardiovascular Surgery , The Second Xiangya Hospital, Central South University , Changsha , China.

Cancer Biology & Therapy
|December 2, 2016
PubMed
Summary
This summary is machine-generated.

A rare primary cardiac tumor, peripheral primitive neuroectodermal tumor, was successfully resected in a 53-year-old female. Follow-up showed no recurrence, indicating successful treatment for this cardiac neoplasm.

Keywords:
Cardiac tumorcomputed tomographymalignantno recurrencepericardial effusionperipheral primitive neuroectodermal tumorresection surgery

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Area of Science:

  • Cardiology
  • Oncology
  • Pathology

Background:

  • Primary cardiac tumors are rare.
  • Peripheral primitive neuroectodermal tumors (PNETs) are exceptionally rare in the heart.

Observation:

  • A 53-year-old female presented with a cardiac tumor discovered via CT scan.
  • Cardiac CT revealed a hypo-intense mass extending from the left ventricle.
  • FDG-PET imaging showed no other active lesions, suggesting a localized primary tumor.

Findings:

  • Surgical resection of the cardiac tumor was performed.
  • Pathological diagnosis confirmed primary cardiac peripheral primitive neuroectodermal tumor.
  • The patient recovered well post-surgery.

Implications:

  • Complete resection is a viable treatment for primary cardiac PNETs.
  • Long-term follow-up (24 months) via echocardiography confirmed no tumor recurrence.
  • This case highlights the importance of considering rare tumors in cardiac mass diagnosis.