Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

2.2K
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
2.2K
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

1.9K
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
1.9K
Long-term Potentiation01:25

Long-term Potentiation

3.8K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
3.8K
Long-term Potentiation01:35

Long-term Potentiation

59.1K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
59.1K
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

1.0K
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
1.0K
Long-term Depression01:03

Long-term Depression

3.5K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Objective quality assessment for precision functional MRI data.

Neuron·2026
Same author

Altered neurodevelopmental trajectories of brain structure in Tourette syndrome and Chronic Tic Disorders.

medRxiv : the preprint server for health sciences·2026
Same author

Objective Quality Assessment for Precision Functional MRI Data.

bioRxiv : the preprint server for biology·2026
Same author

Precision functional mapping reveals less inter-individual variability in the child vs. adult human brain.

bioRxiv : the preprint server for biology·2025
Same author

Dennis D.M. O'Leary (1954-2024).

Neuron·2025
Same author

Multisensory naturalistic decoding with high-density diffuse optical tomography.

Neurophotonics·2025

Related Experiment Video

Updated: Mar 11, 2026

A Comparative Approach for Quantitative Cell Counting Studies in Widely Different Mammalian Brains
07:14

A Comparative Approach for Quantitative Cell Counting Studies in Widely Different Mammalian Brains

Published on: January 16, 2026

278

Neural plasticity across the lifespan.

Jonathan D Power1, Bradley L Schlaggar2

  • 1National Institute of Mental Health, Bethesda, MD, USA.

Wiley Interdisciplinary Reviews. Developmental Biology
|December 3, 2016
PubMed
Summary

Brain plasticity, the brain

Area of Science:

  • Neuroscience
  • Developmental Biology

Background:

  • The brain's ability to change, known as neural plasticity, involves the malleability of neuronal connectivity and circuitry.
  • Plasticity encompasses diverse phenomena, with some active throughout life and others specific to early development.

Purpose of the Study:

  • To survey key concepts of neural plasticity.
  • To explore how current neural activity influences future activity and memory.
  • To examine development-specific plasticity mechanisms.

Main Methods:

  • Review of current scientific data and literature on neural plasticity.
  • Conceptual framework integrating lifespan and developmental plasticity.

Main Results:

  • Neural plasticity is a multifaceted process with both continuous and development-exclusive mechanisms.

More Related Videos

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus
05:01

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

Published on: September 20, 2024

841
Whole-cell Patch-clamp Recordings in Brain Slices
07:23

Whole-cell Patch-clamp Recordings in Brain Slices

Published on: June 15, 2016

62.8K

Related Experiment Videos

Last Updated: Mar 11, 2026

A Comparative Approach for Quantitative Cell Counting Studies in Widely Different Mammalian Brains
07:14

A Comparative Approach for Quantitative Cell Counting Studies in Widely Different Mammalian Brains

Published on: January 16, 2026

278
Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus
05:01

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

Published on: September 20, 2024

841
Whole-cell Patch-clamp Recordings in Brain Slices
07:23

Whole-cell Patch-clamp Recordings in Brain Slices

Published on: June 15, 2016

62.8K
  • Current neural activity shapes future patterns, contributing to learning and memory.
  • Developmental stages involve unique plasticity mechanisms crucial for circuit formation.

    • Conclusions:

    • Understanding neural plasticity requires considering both enduring and early-life processes.
    • The interplay between activity-dependent and developmental plasticity is fundamental to brain function.
    • Further research into specific mechanisms can illuminate brain development and adaptation.