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Related Experiment Video

Updated: Mar 10, 2026

Author Spotlight: Optimizing Scorpion Venom Extraction for Antivenom Production
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Rush Venom Immunotherapy in Children.

Ronit Confino-Cohen1, Yossi Rosman1, Arnon Goldberg1

  • 1Allergy and Clinical Immunology Unit, Meir Medical Center, Kfar-Saba, Israel; Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

The Journal of Allergy and Clinical Immunology. in Practice
|December 5, 2016
PubMed
Summary
This summary is machine-generated.

Rush venom immunotherapy (VIT) offers a safe and effective treatment for Hymenoptera venom allergies in children. This rapid approach proved as safe as conventional VIT but demonstrated superior efficiency in achieving treatment goals.

Keywords:
Bee venom allergyHymenoptera venom allergyRush venom immunotherapy

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Area of Science:

  • Allergy and Immunology
  • Pediatric Medicine
  • Clinical Research

Background:

  • Hymenoptera venom immunotherapy (VIT) is a proven treatment for venom allergies.
  • Data on the safety and efficacy of rush VIT in pediatric populations are limited.

Purpose of the Study:

  • To assess the safety and effectiveness of rush VIT in children and adolescents.
  • To compare rush VIT with conventional VIT in a pediatric cohort.

Main Methods:

  • A 3-day build-up phase was used for both conventional and rush VIT.
  • Participants included children under 16 with systemic reactions (beyond skin) and 16-18 year olds with any systemic reaction.
  • Eighty-four children opted for rush VIT, with 70 allergic to bee venom.

Main Results:

  • No significant difference in the incidence or severity of systemic reactions during the build-up phase between rush and conventional VIT.
  • Rush VIT showed improved efficiency, with a higher percentage of patients reaching the 100 mcg maintenance dose (98.8% vs. 90.7%).
  • P-value of .04 indicated a statistically significant difference in achieving the maintenance dose.

Conclusions:

  • Rush VIT is a safe alternative to conventional VIT for pediatric patients.
  • Rush VIT demonstrates enhanced efficiency in treating Hymenoptera venom allergy in children.