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Reversible cerebral vasoconstriction syndrome.

Michael Perdices1,2, Geoffrey Herkes1,3

  • 1a Department of Neurology , Royal North Shore Hospital , Sydney , Australia.

Neuropsychological Rehabilitation
|December 6, 2016
PubMed
Summary
This summary is machine-generated.

Reversible cerebral vasoconstriction syndrome (RCVS) can cause lasting cognitive deficits, even without bleeding. This case highlights potential long-term memory and learning impairments following RCVS.

Keywords:
AngiopathyRCVSneuropsychological impairment

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Area of Science:

  • Neurology
  • Neuropsychology

Background:

  • Reversible cerebral vasoconstriction syndrome (RCVS) is a rare angiopathy causing thunderclap headaches and cerebral artery constriction.
  • While typically resolving within three months, RCVS can sometimes lead to transient neurological signs or, rarely, hemorrhagic complications.

Observation:

  • A 36-year-old woman experienced RCVS triggered by Ear, Nose, and Throat surgery.
  • Her condition resolved quickly with verapamil, with no hemorrhagic events or subsequent radiological abnormalities.

Findings:

  • Despite radiological resolution, 16 months post-RCVS, the patient exhibited significant deficits in memory, learning, cognitive flexibility, and processing speed.
  • These persistent neuropsychological impairments were observed despite the absence of hemorrhagic complications during the RCVS episode.

Implications:

  • This case suggests that persistent cognitive deficits may be an underrecognized feature of RCVS, even in the absence of hemorrhage.
  • The findings challenge the notion that RCVS-related cognitive impairments are solely transient or linked to hemorrhagic events.
  • Further research is needed to understand the mechanisms and prevalence of long-term cognitive sequelae in RCVS.