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Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) - Report 1: Epidemiology and Classification
Elizabeth J Chen1, Muhammad Amir Bin Ismail2, Helen Mi2
1a Yong Loo Lin School of Medicine , National University of Singapore , Singapore.
Ocular Immunology and Inflammation
|December 6, 2016
Summary
This study analyzed ocular inflammation in Singapore, finding anterior uveitis most common. Non-infectious causes slightly outnumbered infectious ones, with tuberculosis and viral infections being prevalent.
Area of Science:
- Ophthalmology
- Immunology
- Epidemiology
Background:
- Ocular inflammation presents diverse clinical manifestations.
- Understanding its epidemiology is crucial for effective management.
- The Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) database provides valuable data.
Purpose of the Study:
- To describe the epidemiology and classification of ocular inflammation.
- To analyze patterns at a tertiary eye care center in Singapore.
- To identify common causes and types of ocular inflammatory diseases.
Main Methods:
- Retrospective cohort study design.
- Utilized data from the OASIS database (2004-2015).
- Included consecutive new cases of ocular inflammation.
Main Results:
- 2200 patients were analyzed.
- Anterior uveitis was the most frequent diagnosis (55.9%).
- Established etiologies included presumed tuberculosis (7.2%), cytomegalovirus (6.9%), and herpetic infections (6.3%).
Conclusions:
- Ocular inflammation patterns in Singapore resemble both Western and Asian populations.
- Anterior uveitis is the predominant form.
- Non-infectious etiologies were slightly more common than infectious ones.
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