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[Community-acquired pneumonia].

B Kemmerich1, M Rahlwes, H Vogel-Hartmann

  • 1Abteilung für Kardiologie und Pneumologie, Freien Universität, Berlin.

Deutsche Medizinische Wochenschrift (1946)
|September 29, 1989
PubMed
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Pneumonia diagnosis can be improved by testing for pneumococcal antigen in sputum. Legionella is a common cause of community-acquired pneumonia, requiring broad species testing for accurate diagnosis.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Clinical Medicine

Background:

  • Pneumonia remains a significant cause of hospital admissions and mortality.
  • Identifying the causative organism is crucial for effective treatment and understanding disease epidemiology.
  • Previous diagnostic methods may have limitations in accurately identifying all common pathogens.

Purpose of the Study:

  • To investigate the causative organisms of pneumonia in hospitalized patients.
  • To evaluate the effectiveness of different diagnostic methods for specific pathogens.
  • To assess the epidemiological significance of Legionella and Pneumococcus in pneumonia cases.

Main Methods:

  • Prospective analysis of 212 patients admitted with pneumonia between 1982-1983 and 1985-1986.

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  • Identification of causative organisms using culture and immunological techniques (antigen/antibody detection).
  • Specific evaluation of pneumococcal antigen detection in sputum, urine, and serum.
  • Main Results:

    • The causative organism was identified in 60% (127/212) of patients.
    • Streptococcus pneumoniae (pneumococcus) was the most frequent pathogen (n=64).
    • Legionella species were identified in 15 patients; mixed infections occurred in 11 patients, often with pneumococci. 24 deaths (11.3%) were recorded.

    Conclusions:

    • Pneumococcal antigen detection in sputum improves etiological diagnosis of pneumonia.
    • Legionella is a frequent cause of non-hospital-acquired pneumonia.
    • Comprehensive serological testing across multiple Legionella species is necessary for accurate diagnosis of Legionnaire's disease.