Related Experiment Video
Updated: Mar 10, 2026

08:15
3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects
Published on: August 4, 2020
7.1K
Rapid prototyped patient specific guiding implants in critical mandibular reconstruction
Patricia Stoor1, Anni Suomalainen2, Karri Mesimäki1
1Department of Oral and Maxillofacial Surgery, Helsinki University Central Hospital, Helsinki, Finland.
Summary
Patient-specific implants (PSI) offer a promising solution for reconstructing large mandible defects after tumor resection. This method aids in restoring jaw function and aesthetics, potentially reducing complications associated with traditional methods.
Area of Science:
- Oral and Maxillofacial Surgery
- Biomaterials Engineering
- Medical Device Design
Background:
- Large mandible defects from tumors necessitate immediate reconstruction for functional and aesthetic restoration.
- Traditional reconstruction methods can involve donor site morbidity and lengthy procedures.
Purpose of the Study:
- To evaluate the efficacy and outcomes of immediate mandible reconstruction using patient-specific implants (PSI).
- To assess the feasibility of using computer-aided design and rapid prototyping for creating PSI for mandibular defects.
Main Methods:
- Prospective study involving 14 patients with large mandible tumors requiring continuity resection.
- Utilized 15 computer-aided design (CAD) and rapid prototyped patient-specific implants (PSI) for reconstruction.
- PSI scaffolds were filled with beta-tricalcium phosphate granules and autologous bone; microvascular reconstruction was performed in 12 cases.
Main Results:
- Uneventful healing occurred in nine out of 15 cases.
- Complications included one microvascular flap loss, one revision for mucosal perforation, and four major complications (mucosal perforation leading to infection and PSI removal).
- Average clinical follow-up was 33 months, and radiological follow-up was 21 months.
Conclusions:
- Patient-specific implants (PSI) represent a promising approach for large mandible reconstructions post-resection.
- Benefits include potentially fewer donor site complications and a more precise, expedited surgical process.

