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Quantification and Analysis of Leaflet Flutter on Biological Prosthetic Cardiac Valves
Artur H de F Avelar1, Jean A Canestri1, Camila Bim1
1Mechanical Engineering Department, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Artificial Organs
|December 8, 2016
Summary
Fluttering in biological heart valves, often caused by calcification and fatigue, can be quantified. This study developed a method to measure flutter frequencies, finding bovine pericardial valves perform better than porcine ones, aiding in extending valve lifespan.
Area of Science:
- Biomedical Engineering
- Cardiovascular Research
- Materials Science
Background:
- Biological cardiac valves (porcine/bovine pericardium) have limited lifespan due to calcification and fatigue.
- Leaflet flutter, an understudied oscillation, can accelerate valve degradation and cause regurgitation.
Purpose of the Study:
- To develop a method for quantifying flutter frequencies in biological heart valves at full opening.
- To investigate factors influencing flutter and establish a predictive model for bioprosthesis durability.
Main Methods:
- Simulated heart flow test bench with high-speed camera (2000 fps) filming.
- Motion capture software to analyze leaflet vibration frequencies and amplitudes.
- Dimensionless analysis relating valve properties to flutter onset speed.
Main Results:
- Flutter oscillations detected in the range of 200 Hz with average amplitudes of 0.4 mm.
- Larger diameter valves exhibited lower flutter values.
- Bovine pericardial valves demonstrated superior performance over porcine valves.
Conclusions:
- A novel method for quantifying flutter frequencies and predicting flutter occurrence in bioprostheses was established.
- Findings provide a new tool to enhance the durability and lifespan of biological prosthetic valves.
- Understanding flutter is crucial for improving biological valve design and patient outcomes.
