Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perfusion techniques for an 800 g premature neonate undergoing Arterial Switch Procedure for Transposition of the Great Arteries★.

The journal of extra-corporeal technology·2024
Same author

A Comparison of Voice Recognition Program and Traditional Keyboard Charting for Nurse Documentation.

Computers, informatics, nursing : CIN·2021
Same author

Impact of a Pharmacist-Driven Penicillin Allergy Skin Testing Protocol on Antimicrobial Stewardship in a Tertiary Care Hospital.

Hospital pharmacy·2021
Same author

Increased cerebral mitochondrial dysfunction and reactive oxygen species with cardiopulmonary bypass.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2020
Same author

Comparison of three autotransfusion devices for utilization in the pediatric population.

Perfusion·2020
Same author

Improving denials management at the enterprise level.

Healthcare financial management : journal of the Healthcare Financial Management Association·2015

Related Experiment Video

Updated: Mar 10, 2026

Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium
12:08

Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium

Published on: February 14, 2022

3.5K

Implementation of a Pharmacist-Directed Antimicrobial Stewardship Protocol Utilizing Rapid Diagnostic Testing.

Angel Heyerly, Ron Jones, Gordon Bokhart

    Hospital Pharmacy
    |December 9, 2016
    PubMed
    Summary

    Rapid identification of gram-positive bacteria, combined with pharmacist intervention, significantly cut time to optimal antibiotic therapy. This approach enhances antimicrobial stewardship and patient outcomes.

    Keywords:
    antimicrobial stewardshipautomated microarray nucleic acid testgram-positive bacteremiapharmacist intervention

    More Related Videos

    One-day Workflow Scheme for Bacterial Pathogen Detection and Antimicrobial Resistance Testing from Blood Cultures
    08:30

    One-day Workflow Scheme for Bacterial Pathogen Detection and Antimicrobial Resistance Testing from Blood Cultures

    Published on: July 9, 2012

    26.1K
    Author Spotlight: Accelerating Diagnostic Accuracy with Direct Identification of Gram-Negatives from Blood Culture Bottles
    09:07

    Author Spotlight: Accelerating Diagnostic Accuracy with Direct Identification of Gram-Negatives from Blood Culture Bottles

    Published on: May 24, 2024

    1.5K

    Related Experiment Videos

    Last Updated: Mar 10, 2026

    Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium
    12:08

    Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium

    Published on: February 14, 2022

    3.5K
    One-day Workflow Scheme for Bacterial Pathogen Detection and Antimicrobial Resistance Testing from Blood Cultures
    08:30

    One-day Workflow Scheme for Bacterial Pathogen Detection and Antimicrobial Resistance Testing from Blood Cultures

    Published on: July 9, 2012

    26.1K
    Author Spotlight: Accelerating Diagnostic Accuracy with Direct Identification of Gram-Negatives from Blood Culture Bottles
    09:07

    Author Spotlight: Accelerating Diagnostic Accuracy with Direct Identification of Gram-Negatives from Blood Culture Bottles

    Published on: May 24, 2024

    1.5K

    Area of Science:

    • Clinical Microbiology
    • Antimicrobial Stewardship
    • Health Informatics

    Background:

    • Timely identification of gram-positive bacteria from blood cultures is crucial for effective antibiotic treatment.
    • Current methods often involve lengthy traditional culture techniques, delaying optimal therapy.
    • Rapid diagnostic technologies offer a potential solution to expedite bacterial identification.

    Purpose of the Study:

    • To evaluate the impact of rapid diagnostic testing for gram-positive bacteria combined with a pharmacist-led stewardship protocol.
    • To assess improvements in time to optimal antibiotic therapy and antimicrobial use.
    • To determine the effectiveness of this integrated approach in a tertiary-care setting.

    Main Methods:

    • Rapid nucleic acid-based diagnostic testing was applied to positive gram-positive blood cultures.
    • Pharmacists actively intervened by notifying prescribers and recommending targeted antimicrobial therapy.
    • Primary outcomes included time to optimal antibiotic therapy, time antibiotics were avoided, and the percentage of patients receiving timely therapy.

    Main Results:

    • Rapid identification reduced bacterial detection time by 48.5 hours compared to traditional methods (26.8 vs 75.3 hours).
    • The combined approach significantly improved time to optimal antibiotic therapy (8.4 vs 15.4 hours).
    • A higher percentage of patients received antibiotic changes within 2 hours in the intervention group (28% vs 10.5%).

    Conclusions:

    • Rapid bacterial identification coupled with pharmacist intervention markedly reduces time to optimal antibiotic therapy.
    • This integrated strategy significantly increases the proportion of patients receiving appropriate, timely antibiotic treatment.
    • Pharmacist-directed protocols enhance antimicrobial stewardship when combined with rapid diagnostic technologies.