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Updated: Mar 10, 2026

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

Neuro-Sweet Disease Causing Orbital Inflammation.

Parisa Taravati¹

¹Department of Ophthalmology, University of Washington Seattle, Washington USA.

Neuro-Ophthalmology (Aeolus Press)

|December 9, 2016

Summary

This summary is machine-generated.

Neuro-Sweet disease, a rare condition, can cause brain inflammation and skin rashes. This case highlights its potential to cause orbital inflammation, which resolved with corticosteroid treatment.

Keywords:

Neuro-Sweet disease Sweet syndrome orbital cellulitis orbital inflammation

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Area of Science:

Neurology
Ophthalmology
Dermatology

Background:

Neuro-Sweet disease is a rare condition characterized by encephalitis or meningitis and the skin plaques of Sweet syndrome.
Ocular manifestations are known complications, including movement disorders, episcleritis, conjunctivitis, uveitis, and optic disc edema.

Observation:

A patient presented with orbital inflammation, cranial neuropathies, and a skin rash.
The patient had a history of myelodysplastic syndrome.

Findings:

Skin biopsy confirmed the diagnosis of neuro-Sweet disease.
This is the first reported case of neuro-Sweet disease presenting with orbital inflammation.

Implications:

This case expands the known spectrum of ocular manifestations of neuro-Sweet disease.
Systemic corticosteroid therapy appears effective in managing the orbital inflammation associated with neuro-Sweet disease.