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Related Concept Videos

Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

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Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Related Experiment Video

Updated: Mar 10, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
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An unusual mediastinal mass.

J Hardy1, A R Jeyabalan, N Bhatt

  • 1ARL Medford, North Bristol Lung Centre & University of Bristol Brunel Building, Southmead Hospital, Westbury-on-Trym, Bristol BS10 5NB, UK, E-mail andrew.medford@nbt.nhs.uk.

The Journal of the Royal College of Physicians of Edinburgh
|December 9, 2016
PubMed
Summary
This summary is machine-generated.

A rare case of ectopic mediastinal thyroid tissue presented as a mass causing airway compression. Diagnosis was confirmed via endobronchial ultrasound-guided fine needle aspiration, even with negative scintigraphy.

Keywords:
ectopic mediastinal thyroidendobronchial ultrasound-guided fine needle aspirationmediastinal massmediastinumpositron emission tomography

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Area of Science:

  • Endocrinology
  • Thoracic Surgery
  • Diagnostic Imaging

Background:

  • Ectopic thyroid tissue in the mediastinum is exceptionally rare.
  • Most cases are asymptomatic and detected via positive scintigraphy.
  • This case highlights a symptomatic presentation with negative imaging findings.

Observation:

  • A 35-year-old male presented with weight loss, cough, and breathlessness due to a mediastinal mass.
  • Flow volume loops and thyroid function tests were normal; thyroid antibodies were negative.
  • Technetium scintigraphy and PET scans showed no uptake in the mass.

Findings:

  • Endobronchial ultrasound-guided fine needle aspiration definitively diagnosed ectopic mediastinal thyroid tissue.
  • False-negative scintigraphy can occur due to necrosis, malignancy, or substernal location.
  • This underscores the importance of considering ectopic thyroid tissue despite negative imaging.

Implications:

  • Ectopic mediastinal thyroid tissue is a rare but critical differential diagnosis for mediastinal masses.
  • Diagnostic approaches should be tailored to clinical context, especially when imaging is inconclusive.
  • Endobronchial ultrasound-guided fine needle aspiration is a valuable tool for diagnosing such rare conditions.