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Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

POLYPOIDAL CHOROIDAL VASCULOPATHY: A CLINICOPATHOLOGIC STUDY.

Kareem Moussa¹, Michele M Bloomer, Daniel M Schwartz

¹*Department of Ophthalmology, University of California, San Francisco, San Francisco, California; †Department of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, California; and ‡Department of Ophthalmology, Santa Clara Valley Medical Center, San Jose, California.

Retinal Cases & Brief Reports

|December 9, 2016

Summary

This summary is machine-generated.

Polypoidal choroidal vasculopathy can mimic an intraocular mass, causing sudden vision loss. Early diagnosis in East Asian patients with vitreous hemorrhage is crucial.

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Published on: May 26, 2023

Area of Science:

Ophthalmology
Medical Research

Background:

Polypoidal choroidal vasculopathy (PCV) is a subtype of age-related macular degeneration.
PCV can present with varied clinical manifestations, sometimes mimicking other ocular pathologies.

Observation:

A 58-year-old Vietnamese male presented with a blind, painful eye and suspected intraocular mass.
B-scan ultrasonography revealed massive intraocular hemorrhage, precluding definitive diagnosis of a tumor.
Histopathologic examination post-enucleation confirmed polypoidal choroidal vasculopathy.

Findings:

Polypoidal choroidal vasculopathy can present as a blind, painful eye with massive vitreous hemorrhage.
The condition can be misdiagnosed as an intraocular mass due to extensive hemorrhage.
Histopathology is essential for confirming PCV in atypical presentations.

Implications:

PCV should be considered in the differential diagnosis of intraocular masses, especially in patients of East Asian descent.
Rapid progression and irreversible vision loss underscore the importance of timely diagnosis and management.
This case highlights the need for high clinical suspicion for PCV in patients with unexplained vitreous hemorrhage.