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Related Concept Videos

Genetic Screens02:46

Genetic Screens

5.8K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
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Gene Families01:57

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Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
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Related Experiment Video

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Pattern-based Search of Epigenomic Data Using GeNemo
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Exploring FlyBase Data Using QuickSearch.

Steven J Marygold1, Giulia Antonazzo1, Helen Attrill1

  • 1Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.

Current Protocols in Bioinformatics
|December 9, 2016
PubMed
Summary
This summary is machine-generated.

The FlyBase database provides extensive genetic and genomic data for Drosophila research. Its QuickSearch tool offers an intuitive interface for researchers to efficiently access this vast information.

Keywords:
Drosophila melanogasterFlyBaseQuickSearchbiological databasequery tools

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Area of Science:

  • Genomics
  • Bioinformatics
  • Model Organism Research

Background:

  • FlyBase is a comprehensive database for Drosophila genetic, genomic, and functional information.
  • Drosophila melanogaster is a key model organism with a rich research history.
  • Increasing data volume necessitates efficient data retrieval tools.

Purpose of the Study:

  • To describe the functionality of the QuickSearch tool within FlyBase.
  • To enable researchers to rapidly and intuitively query FlyBase data.
  • To improve user access to relevant Drosophila research information.

Main Methods:

  • The QuickSearch tool is integrated into the FlyBase homepage.
  • It features a tabbed interface for major data and annotation classes.
  • The tool is designed for intuitive and rapid data querying.

Main Results:

  • QuickSearch provides a user-friendly way to navigate and search FlyBase.
  • The tool covers major data and annotation classes within the database.
  • Users can gain improved access to data relevant to their research.

Conclusions:

  • The QuickSearch tool enhances the usability of the FlyBase database.
  • Researchers can leverage QuickSearch for more efficient data discovery.
  • This facilitates better utilization of Drosophila research data.