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[Survey of Campylobacter jejuni/coli infection and risk factors in children]
Insights
Campylobacter jejuni/coli is a significant cause of childhood diarrhea in Chengdu. Key risk factors include contact with animals and eating with hands, informing prevention strategies.
Area of Science:
- Microbiology
- Pediatrics
- Epidemiology
Background:
- Campylobacter jejuni/coli is a recognized cause of bacterial gastroenteritis globally.
- Childhood diarrhea remains a major public health concern in many regions, including China.
Purpose of the Study:
- To determine the prevalence of Campylobacter jejuni/coli in children with and without diarrhea in Chengdu.
- To identify risk factors associated with Campylobacter jejuni/coli infection in children.
Main Methods:
- Stool samples from 798 children under 7 were cultured for C. jejuni/coli.
- A case-control study investigated risk factors, matching 53 cases with 159 controls.
Main Results:
- C. jejuni/coli was detected in 9.51% of children with diarrhea and 4.66% without.
- Contact with animals (OR=2.97) and hand-to-mouth food intake (OR=2.71) were significant risk factors.
Conclusions:
- C. jejuni/coli is an important enteric pathogen contributing to childhood diarrhea in Chengdu.
- Findings highlight the need for improved hygiene and animal contact control for prevention.
Abstract:
From March to May 1987, 798 children under 7 years of the outpatients in Chengdu district were examined and their stool samples cultured for Campylobacter jejuni/coli. C. jejuni/coli was isolated from 31 (9.51%) of 326 children with diarrhea and 22 (4.66%) of 472 children with non-diarrhea. The difference was significant (P less than 0.05). This result indicated that C. jejuni/coli is an important pathogen of children diarrhea in Chengdu district. Meanwhile, by inquiry we investigated risk factors related with C. jejuni/coli infections. Case group was consisted of 53 children with C. jejuni/coli positive. For each case, 3 controls were chosen from 745 children with C. jejuni/coli negative and matched according to age (less than 6 month), sex, living place (city or countryside), way of feeding, and whether to have diarrhea or not. The results has shown that contact with animals a week before being ill and habit of intake of food with hands are risk factors of C. jejuni/coli infection of childhood in Chengdu, with an odd ratio of 2.97 and 2.71 respectively. This provides valuable information about the prevention of C. jejuni/coli infection.