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Vogt-Koyanagi-Harada syndrome - current perspectives
Abeir Baltmr1, Sue Lightman2, Oren Tomkins-Netzer3
1Uveitis Service, Moorfields Eye Hospital, London, UK.
Clinical Ophthalmology (Auckland, N.Z.)
|December 10, 2016
Summary
Vogt-Koyanagi-Harada syndrome causes noninfectious panuveitis and vision loss. Early immunosuppressive treatment can halt progression and prevent recurrence.
Area of Science:
- Ophthalmology
- Immunology
- Genetics
Background:
- Vogt-Koyanagi-Harada (VKH) syndrome is a leading cause of noninfectious panuveitis.
- It is an autoimmune condition affecting genetically predisposed individuals.
- Clinical presentation includes bilateral panuveitis, optic disc swelling, and serous retinal detachments.
Approach:
- This review synthesizes current knowledge on VKH syndrome.
- It focuses on diagnostic challenges and therapeutic strategies.
- The review highlights the importance of early intervention.
Key Points:
- Neurological and auditory symptoms often accompany ocular manifestations.
- Prompt treatment with corticosteroids and other immunosuppressants is crucial.
- Adequate treatment can prevent disease recurrence and vision impairment.
Conclusions:
- VKH syndrome requires timely diagnosis and management.
- Immunosuppressive therapy is the cornerstone of treatment.
- Understanding the variable clinical aspects aids in better patient outcomes.
Keywords:
corticosteroidmultifocal choroiditispanuveitisserous retinal detachmentstarry skysunset glow fundusMore Related Videos
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