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Updated: Mar 10, 2026

Preparation of Binary and Ternary Deep Eutectic Systems
Published on: October 31, 2019
Thermodynamic Study of Molecular Interactions in Eutectic Mixtures Containing Camphene
Marcin Okuniewski1, Kamil Paduszyński1, Urszula Domańska1,2
1Department of Physical Chemistry, Faculty of Chemistry, Warsaw University of Technology , Noakowskiego 3, 00-664 Warsaw, Poland.
This study investigates the solid-liquid equilibrium of camphene with various solvents, analyzing trends based on solvent structure and molecular interactions. Thermodynamic models were evaluated for their predictive accuracy in these terpene mixtures.
Area of Science:
- Physical Chemistry
- Thermodynamics
- Chemical Engineering
Background:
- Terpenes are diverse chemicals with broad applications.
- Understanding physical and thermodynamic properties of terpenes and their mixtures is crucial.
Purpose of the Study:
- To conduct a thermodynamic study on solid-liquid equilibrium (SLE) phase diagrams in binary systems.
- To investigate mixtures of (±)-camphene with various solvents including n-alkanes, alcohols, and aromatic compounds.
Main Methods:
- Experimental measurement of solid-liquid equilibrium (SLE) phase diagrams.
- Analysis of SLE data trends based on solvent structure (alkyl chain length, aromaticity) and molecular interactions.
- Modeling of SLE phase diagrams using modified UNIFAC (Dortmund), PC-SAFT, and COSMO-RS.
Main Results:
- Observed trends in SLE data were correlated with solvent structural features and intermolecular forces.
- Comparative analysis of modified UNIFAC, PC-SAFT, and COSMO-RS performance in predicting SLE temperatures.
- Evaluation of model accuracy based on average absolute deviations between predicted and experimental SLE temperatures.
Conclusions:
- The study provides valuable thermodynamic data for terpene mixtures.
- Insights into structure-property relationships for solvent selection in terpene processing.
- Assessment of the predictive capabilities of leading thermodynamic models for complex mixtures.
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