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Updated: Mar 10, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Do patients with submassive pulmonary embolism benefit from thrombolytic therapy?
Ali Ataya1, Jessica Cope2, Abbas Shahmohammadi3
1Pulmonary Hypertension Program, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida, Gainesville, FL, USA.
Abstract:
Despite growing interest in thrombolytic agents to treat submassive pulmonary embolism, their role in this scenario remains controversial. Needed is a way to identify patients with this condition who are at risk of clinical deterioration and who would benefit from thrombolytic therapy. Here, we review the use of thrombolytic agents in submassive pulmonary embolism to help distinguish the risk and benefits of this therapy.
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