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Updated: Mar 10, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
39.6K
Palmoplantar psoriasis.
Burhan Engin1, Özge Aşkın1, Yalçın Tüzün1
1Department of Dermatology, Cerrahpaşa Medical Faculty, İstanbul University, Fatih, İstanbul, Turkey.
Clinics in Dermatology
|December 13, 2016
Summary
Palmoplantar psoriasis, a localized variant affecting hands and feet, causes significant functional impairment. Severity assessment should prioritize daily activity impact over body surface area.
Area of Science:
- Dermatology
- Clinical Medicine
Background:
- Palmoplantar psoriasis is a localized variant of psoriasis, affecting 3-4% of cases.
- It presents with pustular lesions, hyperkeratotic plaques, or both on palms and soles.
- This condition significantly impacts daily activities due to fissures and tissue hardening.
Purpose of the Study:
- To highlight the clinical characteristics of palmoplantar psoriasis.
- To emphasize functional impairment as a key severity indicator.
- To outline current management strategies.
Main Methods:
- Review of clinical presentations and patient-reported functional outcomes.
- Analysis of traditional severity assessment versus functional impairment.
- Evaluation of treatment pathway effectiveness.
Main Results:
- Body surface area is an unreliable measure for palmoplantar psoriasis severity.
- Functional impairment is a more relevant metric for assessing disease impact.
- Topical therapies are the first-line treatment, followed by systemic agents or biologics if needed.
Conclusions:
- Palmoplantar psoriasis requires a shift in severity assessment towards functional impact.
- Management follows a stepwise approach from topical to systemic and biologic therapies.
- Effective management aims to improve quality of life by addressing functional limitations.
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