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Related Concept Videos

Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...

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Updated: May 31, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

Chronic ear pruritus.

Zeynep Altan Ferhatoğlu1, Defne Özkoca2, Yalçın Tüzün1

  • 1İstanbul University-Cerrahpaşa, Cerrahpaşa Medical Faculty, Department of Dermatology, İstanbul, Turkey.

Clinics in Dermatology
|May 29, 2026
PubMed
Summary
This summary is machine-generated.

Chronic ear pruritus, persistent itching of the ear, has diverse causes including skin conditions, infections, and systemic diseases. Effective management requires accurate diagnosis and tailored treatments for improved quality of life.

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Area of Science:

  • Dermatology
  • Otolaryngology
  • Internal Medicine

Background:

  • Chronic ear pruritus, defined as itching lasting over six weeks, is a prevalent condition impacting patient quality of life.
  • It presents a broad differential diagnosis encompassing dermatologic, otolaryngologic, and systemic etiologies.
  • Common dermatologic causes include psoriasis, seborrheic dermatitis, and atopic dermatitis, while otolaryngologic factors involve otomycosis and chronic otitis externa.

Purpose of the Study:

  • To review the differential diagnosis of chronic ear pruritus.
  • To discuss diagnostic approaches, emphasizing medical history and physical examination.
  • To outline current and emerging management strategies for chronic ear pruritus.

Main Methods:

  • Literature review of chronic ear pruritus.
  • Analysis of diagnostic criteria and patient history components.
  • Synthesis of treatment modalities, including topical, systemic, and novel therapies.

Main Results:

  • Chronic ear pruritus stems from various conditions: dermatologic (psoriasis, dermatitis), otolaryngologic (otomycosis, otitis externa), and systemic diseases (diabetes, liver/kidney disorders).
  • Diagnosis relies on thorough history and physical exams, considering both local and systemic factors.
  • Management varies based on etiology, utilizing corticosteroids, antifungals, immunomodulators, and allergen avoidance.

Conclusions:

  • Accurate diagnosis is crucial for effective management of chronic ear pruritus.
  • Treatment strategies are diverse, ranging from topical agents to systemic immunomodulators and biologics for refractory cases.
  • Addressing underlying causes and identifying triggers, like allergens in contact dermatitis, are key to alleviating persistent ear itching.