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Updated: Mar 10, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

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Amiodaron in atrial fibrillation: post coronary artery bypass graft

Paria Habibollahi1, Shahrzad Hashemi Jam2, Samad Shams Vahdati2

  • 1Pharmacology and Toxicology Department, Tabriz University of Medical Science, Tabriz, Iran.

World Journal of Emergency Medicine
|December 13, 2016
PubMed

Insights

Amiodarone effectively prevents atrial fibrillation (AF) after coronary artery bypass graft (CABG) surgery. While its therapeutic use for AF is less studied, prophylaxis remains the primary strategy.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Pharmacology

Background:

  • Atrial fibrillation (AF) is a frequent complication after cardiac surgery, particularly coronary artery bypass graft (CABG).
  • This review categorizes the prophylactic and therapeutic uses of Amiodarone in CABG patients.
  • Identifying optimal strategies for AF management post-CABG is crucial.

Approach:

  • A comprehensive literature search was conducted across Google Scholar, PubMed, and Cochrane Library databases.
  • Articles published between 1970 and 2010 focusing on Amiodarone in CABG and cardiac surgery were reviewed.
  • 30 relevant articles were selected from an initial pool of 1,561 studies.

Key Points:

  • Evidence strongly supports Amiodarone's prophylactic use in reducing AF incidence post-CABG.
  • Therapeutic application of Amiodarone for established AF post-CABG is less documented.
  • Prophylaxis may mitigate AF occurrence, while therapeutic use might reduce side effects but shows no significant impact on hospital stay length.

Conclusions:

  • Currently, no definitive therapeutic method for post-cardiac surgery AF is established.
  • Prophylaxis with Amiodarone is the predominant approach recommended in medical literature for AF prevention after CABG.
  • Further research is needed to define optimal therapeutic strategies for AF in this patient population.
Abstract

Keywords:
Lateral positionPulmonary aspirationSemi-lateral position

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