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[The Basic-Symptom Concept and its Influence on Current International Research on the Prediction of Psychoses]
Insights
The basic symptom approach offers early detection of psychosis by identifying the earliest signs of the disorder. These basic symptoms may reveal crucial information for future neurobiological research into psychosis development.
Area of Science:
- Psychiatry
- Neuroscience
- Psychology
Background:
- Early detection of psychosis is crucial for intervention.
- The ultra-high risk (UHR) approach identifies individuals at immediate risk.
- The basic symptom approach targets the earliest phenomenological signs of psychosis development.
Purpose of the Study:
- To review the development and assumptions of the basic symptom concept.
- To summarize research on the specificity and psychosis-predictive value of basic symptoms.
- To explore the link between basic symptoms and neurobiological underpinnings of psychosis.
Main Methods:
- Literature review of studies on basic symptoms.
- Analysis of research on basic symptoms across different age groups.
- Introduction to recent neuroimaging studies relevant to the basic symptom concept.
Main Results:
- Basic symptoms are increasingly recognized for early psychosis detection.
- Studies show varying specificity and predictive value of basic symptoms depending on age.
- Neuroimaging findings support basic symptoms as direct expressions of underlying cerebral changes.
Conclusions:
- Basic symptoms are valuable for the earliest possible detection of psychosis.
- Basic symptoms may serve as key indicators for future neurobiological research into psychosis etiology.
- The basic symptom concept offers insights into the psychopathology of psychosis.
Abstract:
The early detection of psychoses has become increasingly relevant in research and clinic. Next to the ultra-high risk (UHR) approach that targets an immediate risk of developing frank psychosis, the basic symptom approach that targets the earliest possible detection of the developing disorder is being increasingly used worldwide. The present review gives an introduction to the development and basic assumptions of the basic symptom concept, summarizes the results of studies on the specificity of basic symptoms for psychoses in different age groups as well as on studies of their psychosis-predictive value, and gives an outlook on future results. Moreover, a brief introduction to first recent imaging studies is given that supports one of the main assumptions of the basic symptom concept, i. e., that basic symptoms are the most immediate phenomenological expression of the cerebral aberrations underlying the development of psychosis. From this, it is concluded that basic symptoms might be able to provide important information on future neurobiological research on the etiopathology of psychoses.
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