Related Experiment Video
Updated: Mar 10, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
Acute interstitial nephritis induced by Solanum nigrum
Sung Sik Oh1, Myung Woo Choi1, Mi Rim Choi1
1Nephrology Division, Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea.
This study reports the first case of acute interstitial nephritis (AIN), a reversible kidney injury, caused by ingesting Solanum nigrum. The patient recovered successfully with corticosteroid treatment.
Area of Science:
- Nephrology
- Toxicology
- Ethnobotany
Background:
- Acute interstitial nephritis (AIN) is a significant cause of reversible acute kidney injury.
- Solanum nigrum (S. nigrum) is a medicinal plant with reported toxic effects, including anticholinergic symptoms.
- No previous cases of AIN attributed to S. nigrum have been documented.
Purpose of the Study:
- To report the first biopsy-confirmed case of acute interstitial nephritis following Solanum nigrum ingestion.
- To highlight the potential nephrotoxicity of Solanum nigrum.
Main Methods:
- Case report of a patient presenting with symptoms after S. nigrum consumption.
- Biopsy confirmation of acute interstitial nephritis.
- Treatment with corticosteroid therapy.
Main Results:
- The patient was diagnosed with biopsy-confirmed acute interstitial nephritis.
- The patient showed successful recovery after treatment with corticosteroids.
Conclusions:
- Solanum nigrum ingestion can lead to acute interstitial nephritis.
- Corticosteroid therapy is an effective treatment for S. nigrum-induced AIN.
- This case expands the known adverse effects of Solanum nigrum.
More Related Videos
07:38Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
Published on: May 6, 2018
14:18Author Spotlight: Investigating the Potential of Chinese Herbal Medicinal Active Dioscin in Treating IgA Nephropathy
Published on: October 13, 2023
Related Concept Videos
Acute Pyelonephritis I: Introduction
Acute Kidney Injury II: Pathophysiology
Nephrotic Syndrome I : Introduction
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury I: Introduction